ImmuneSensor was founded based on the seminal research conducted by Dr. Zhijian “James” Chen at the University of Texas, Southwestern (UTSW). In 2012, his groundbreaking discovery of the cyclic GMP-AMP synthases (cGAS) enzyme and the secondary messenger, cyclic GMP-AMP (cGAMP), quickly spawned the scientific community’s interest and subsequent research into the role of the cGAS-STING pathway in innate immunity. The importance of the pathway in activating the immune system and its broad applicability in many diseases is now widely recognized.

Since our Company’s founding and in-licensing of our intellectual property portfolio from UTSW shortly thereafter, our team has built a promising pipeline of STING agonists and cGAS inhibitors with first- and best-in-class potential.